The ABCDEs of Melanoma Detection
Key Facts
- 99% five-year survival rate for melanoma detected at stage I
- 1 in 5 Americans will develop skin cancer by age 70
- 6mm is the diameter threshold in the ABCDE rule (size of a pencil eraser)
- 50% of melanomas are self-detected by patients or their partners
Melanoma is the most serious type of skin cancer, but when detected early, the survival rate exceeds 99%. Israel has one of the highest melanoma rates globally due to its high UV index, making regular self-examinations essential.
The ABCDE Rule
A - Asymmetry: One half of the mole doesn't match the other half.
B - Border: The borders are irregular, ragged, blurred, or notched.
C - Color: The color is not uniform and may include shades of brown, black, pink, red, white, or blue.
D - Diameter: The spot is larger than 6mm (about the size of a pencil eraser), although melanomas can sometimes be smaller.
E - Evolving: The mole is changing in size, shape, color, or elevation, or new symptoms appear such as bleeding, itching, or crusting.
“The ABCDE rule is a simple framework that saves lives. I encourage every patient to perform monthly self-examinations and to trust their instincts when something on their skin looks different.”
When to See a Dermatologist
Schedule an appointment if you notice any mole that meets one or more of the ABCDE criteria, a new mole appearing after age 30, or any skin lesion that bleeds, itches, or won't heal. If you're at higher risk (fair skin, history of sunburns, family history of melanoma), annual full-body skin exams are recommended.
Prevention in Israel
Given Israel's intense sun exposure, daily sunscreen (SPF 30+), protective clothing, and avoiding peak UV hours (10 AM - 4 PM) are essential prevention strategies.
Sources & References
Medical Disclaimer
This article is for informational purposes only and does not constitute medical advice. Always consult a qualified dermatologist for diagnosis and treatment. The information provided should not be used for self-diagnosis or as a substitute for professional medical care.
About the Author

M.D., Dermatologic Surgery & Mohs Specialist, ACMS Fellow
Dr. Yehonatan Kaplan is a dermatology specialist with a US-trained fellowship in Mohs micrographic surgery and dermatologic oncology. He is a Fellow of the American College of Mohs Surgery (ACMS) and a member of the ASDS, with experience in over 1,000 Mohs procedures.
Medically reviewed on February 28, 2026
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